Alarm about North Korea has spiked. Earlier this month, the North claimed to have successfully test-launched an intercontinental ballistic missile that could hit Alaska. Some experts estimate that North Korea is now 18 to 36 months away from launching a missile able to reach Los Angeles.

President Trump has warned that a "major, major conflict" with North Korea is possible. His closest advisers have said that "the era of strategic patience is over".

So, in this week's Inquiry, we take a look at the two sides' war plans and ask: what would war with North Korea look like?

Producer: Sarah Shebbeare Presenter: Neal Razzell

(image: A combined fire demonstration of the North Korean People's Army celebrating their 85th anniversary on 26 April 2017. Credit: STR/AFP/Getty Images)

Every single second, 20,000 single-use drinking bottles are sold around the world. That is more than a million pieces of non-biodegradable rubbish produced every minute. And as demand grows in developing economies, so will the mountains of waste, with much of it ending up in the ocean.

We learn how the invention of the plastic bottle spawned an industry that has quickly got us hooked. We hear the consequences of our addiction from the man who has dedicated his life to The Great Pacific Garbage Patch. And, with one estimate that by 2050 there will be more plastic in our oceans than fish, we ask if we now need a radical solution. Is it time to ban the plastic bottle?

Presenter: James Fletcher Producers: Simon Maybin and Sarah Shebbeare

(Photo: A bottle of water sits on the floor inside a recycling facility. Credit: Getty Images)

"This structure has novel features, which are of considerable biological interest." It was perhaps the greatest understatement of all time - the announcement more than six decades ago of the discovery of the shape of a single human DNA. The double-helix structure is now one of the world's most recognisable icons. Knowledge of it has transformed the fight against everything from disease to crime.

That revolution was brought to us by an elite. It took the world's most eminent scientists, backed by the treasuries of the United States, the United Kingdom and private markets to go from the discovery of that one gene, in 1953, to map the more than 22,000 genes that make up a human being in 2000. Mapping the genome, as it was known, was likened to "learning the language in which God created life."

Genetic research has since become democratised. Incredible new technologies now allow labs all over the world to not only learn the language of creation, but to write it...and edit it. Do-it-yourself gene editing kits are available online for less than $100. Gene editing offers breathtaking promise - eliminating disability and disease. But the rapid spread of this powerful technology is leading some who've been at the forefront of the research to warn against unintended consequences, and question whether the rush for miracle cures could bring hellish side-effects.

So this week, The Inquiry asks, Is Gene Editing Out of Control?

(Photo: CRISPR CAS 9 Clustered regularly inter spaced short palindromic repeats. segments of prokaryotic DNA containing short repetitions of base sequences. gene editing, genome editing. Credit: Shutterstock)

The tiny state behind a global diplomatic feud.

Qatar's landmass is so small it could fit into the UK 20 times over. Its citizen population is just a few hundred thousand. Yet this desert country finds itself at the centre of a geopolitical dispute, with its powerful neighbour Saudi Arabia leading a blockade against it and President Donald Trump firing off critical Tweets.

So how did this bantam-weight state end up slogging it out with the world's heavyweights? In other words, what's so special about Qatar?

Presenter: James Fletcher Producer: Simon Maybin and Sarah Shebbeare

(image: Doha city skyline, with armoured vehicles, Qatar. Credit: Karim Jaafar/Getty images)

“Humans are the only species that willingly deprive themselves from sleep”. Ever since fire was discovered, we have traded off sleep time for other activities - from creating stone tools to partying. As our technology progressed, the list of things to do rather than sleep just got longer. But with sleep deprivation now a growing health problem, could we be reaching our limits? Or is tiredness part of our condition?

In this week’s programme, an evolutionary biologist, a historian and a neuroscientist give us their take on whether we are now any more tired than our ancestors. We hear what makes human sleep unique and how it has evolved in surprising ways. And finally we hear from a woman with a dream – that we may never have to sleep again.

Producer: Estelle Doyle and Sarah Shebbeare Presenter: James Fletcher

(Photo: A woman shows signs of tiredness as she counts ballot cards. Credit: Leon Neal/Getty Images)

China is currently developing the biggest infrastructure initiative of all time. Called the Belt and Road initiative, the trillion dollar plans involve working with other Asian countries to build hundreds of new roads, high speed trains, ports and pipelines across continent to mimic the ancient Silk Road trading routes. The project offers a clear economic opportunity, but the diplomatic ties that form as a result could have the potential to change the current world order.

Presenter: Ruth Alexander Producer: Kate Lamble

(image: Local people control their sheep and goats on the Karakoram highway in northern Pakistan, part of the new Silk Road. Credit: Aamir Queeshi/AFP/ Getty Images)

On 12 June 2017 thousands of protesters took to the streets in over 160 towns and cities across Russia. Opposition leader Alexei Navalny called on people to march against corruption from Kaliningrad in the west to Yuzhno-Sakhalinsk in the east, in bustling cities and significantly, in rural towns where support for President Putin is strong. This is unusual. Protests are usually restricted to the urban elites in Moscow. So who is Navalny and how has he managed to bring so many people out on the streets?

Our expert witnesses assess the strength of the opposition movement in Russia. They explain that the protests reveal a greater threat to Putin. The mobilisation of a young generation who do not believe what they see on state TV and are turning to opposition politics online instead.

Presenter: Ruth Alexander Producers: Phoebe Keane and Estelle Doyle

(Photo: Russian opposition leader Alexei Navalny speaks during a rally in Lyublino, a suburb of Moscow, 20 September 2015. Credit: Getty Images)

When violent jihadis struck London last Saturday, the rolling news networks kicked quickly into action. The story became front-page news around the world and dominated the UK's news media for days, with ever more information on the attack, the victims and the perpetrators. It was shocking, horrific - and perhaps also exactly what the terrorists wanted.

Terrorists rely on the world's media to spread their message of fear and their ideology. Maybe if there was less media coverage of such attacks, it would frustrate the people behind them. We look at four democratic countries where attempts have been made to limit the media impact of terrorism. Drawing on the lessons learnt, how do you report terrorism?

Presenter: Ruth Alexander Producer: Simon Maybin and Phoebe Keane

(Photo: Various newspapers spread out headlining the London Terror attacks)

Many of us find our jobs stressful, underpaid and the hours too long. But few would complain about work being less physically strenuous than in the past. And yet, new research shows that the decline in physical activity at work is key to explaining the obesity epidemic. So - is work now too easy? And if it is, can this be reversed? Producers: Estelle Doyle and Phoebe Keane Presenter: Michael Blastland

(Photo: Office workers at desks using computers in an office. Credit: Getty Images)

Does the experience of poverty actually take a physical toll on your brain? The Inquiry investigates the scientific claims that being poor affects how our brains work.

It's well known that children from poorer backgrounds do worse at school. And adults who are poor are often criticised for making bad life decisions - ones that don't help them in the long-term.

Some say the problems are rooted in the unfair way our society functions. Others argue it's simple genetics. But a growing body of research suggests that something else may be going on too.

The Inquiry assesses the evidence and asks: does poverty change the way we think?

Presenter: Ruth Alexander Producers: Simon Maybin and Phoebe Keane

(Photo: Concept of human intelligence with human brain on blue background. Credit: Shutterstock)

Brexit showed that the issue is now among the most important for British voters. And that’s likely to continue in June’s UK general election, as major parties have made their positions on immigration central to their campaigns. And yet for decades, immigration was a no-go area for mainstream debate. Following racial tensions in the 1960s, it came to be perceived as a proxy for racism. Today it is one of the most salient issues in British politics. What changed?

Producer: Estelle Doyle Presenter: Ruth Alexander

(Photo: Border Force check the passports of passengers arriving at Gatwick Airport in London, England. Credit: Getty images)

Once the richest country in South America, Venezuela is now in deep economic crisis.

Children in school are fainting from hunger; patients are dying from the lack of basic medicine. As prices spiral out of control, cash is carried not in wallets, but in backpacks. Street protests over the crisis are growing in size and frequency - and the government's response becoming ever more authoritarian.

Yet in 1970, Venezuela was among the wealthiest countries in the world. It was held up as a beacon of democracy and stability - an example of a successful developing economy that turned oil resource wealth into riches. So what went wrong? How did Venezuela go from so rich to so poor?

Presenter: Linda Yueh Producer: Simon Maybin

(Photo: A father and daughter rest while someone holds their place before sunrise in a long line to buy basic foodstuffs at a supermarket in San Cristobal, Venezuela. Credit: Getty Images)